What is Statins – Statin Drug

“Statins” is a class of cholesterol meds. Statins drugs lower the level of cholesterol in the blood by reducing the production of cholesterol by the liver. (The other source of cholesterol in the blood is dietary cholesterol.) Statins block the enzyme in the liver that is responsible for making cholesterol. This enzyme is called hydroxy-methylglutaryl-coenzyme A reductase (HMG-CoA reductase). Scientifically, statins are referred to as HMG-CoA reductase inhibitors.

Benefits of Statins

Most statins successfully help lower low-density lipoproteins, also known as LDL or “bad” cholesterol. Lowering your cholesterol levels with statins helps decrease your risk of stroke, heart attack, and other vessel-related diseases. “They work better than any other cholesterol treatment,” says Richard N. Fogoros, M.D., a cardiologist and former professor of medicine.

Statins offer other benefits besides lowering your cholesterol. For example, they help stabilize the blood vessel lining, which benefits the whole body. This also makes plaque less likely to rupture in the heart, lowering the risk of a heart attack. Statins also help to relax the blood vessels, which leads to a decrease in blood pressure.

List of Statins Drug (maybe Cholesterol Meds too)

  • atorvastatin (Lipitor),
  • fluvastatin (Lescol, Lescol XL),
  • lovastatin (Mevacor, Altoprev),
  • pravastatin (Pravachol),
  • rosuvastatin (Crestor),
  • simvastatin (Zocor), and
  • pitavastatin (Livalo).

read also high cholesterol in kids is common

For what conditions are statins used?

Statins are used for preventing and treating atherosclerosis that causes chest pain, heart attacks, strokes, and intermittent claudication in individuals who have or are at risk for atherosclerosis.

Risk factors for atherosclerosis include:

  • Abnormally elevated cholesterol levels
  • A family history of heart attacks (particularly at a young age)
  • Increasing age
  • Diabetes
  • High blood pressure
  • Obesity

Most individuals are placed on statins because of high levels of cholesterol. Though reduction of cholesterol is important, heart disease is complex and, as discussed previously, other factors such as inflammation may play a role. Thirty-five percent of individuals who develop heart attacks do not have high blood cholesterol levels, yet most of them have atherosclerosis. This means that high levels of cholesterol are not always necessary for atherosclerotic plaques to form.

Because it is not clear which effect of statins drug is responsible for their benefits, the goal of treatment with statins should not be only the reduction of cholesterol to normal levels, but rather the prevention of the complications of atherosclerosis (angina, heart attacks, stroke, intermittent claudication, and death). This concept is important because it allows for individuals who have or are at risk for atherosclerosis and not have high levels of cholesterol. That condition not recommended for treatment with statins. Statins, like angiotensin converting enzyme inhibitors (ACE inhibitors), are an important class of drugs because they have been shown to reduce the incidence of heart attacks, strokes, and death.

What are the side effects of statins (Statins side Effect)?

The most common side effects are:

  • headache
  • nausea
  • vomiting
  • constipation
  • diarrhea
  • rash
  • weakness
  • muscle pain

Clear about statins, now we discuss about benefit for reduce Heart Attack. Describe above statins has effect to lower cholesterol. Low level of cholesterol make blood stream in good condition. This benefit make hearth reduce his stressing. So make hearth attack probability lower too. this news is a good news for hearth attack phobia.

 

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